RReACT Database
The Repository of Registered Analgesic Clinical Trials (RReACT) database provides a snapshot of registered analgesic clinical trials and a scorecard for public availability of results. An overview of the RReACT database is provided by Greene et al. (2012), an update and global expansion is described by Munch et al. (2014), and the inclusion of two additional chronic pain conditions is presented by Dufka et al. (2015). Links to websites listed in the database may not still be active, and some studies may have had full publication of results since the most recent updating of the database. Links to the most recent version of the database follow:
Complex regional pain syndrome
Painful diabetic peripheral neuropathy (DPN) database
Postherpetic neuralgia (PHN) database
Dufka FL, Munch T, Dworkin RH, Rowbotham MC. Results availability for analgesic device, complex regional pain syndrome, and post-stroke pain trials: comparing the RReADS, RReACT and RReMiT databases. Pain, 2015;156:72-80.
Greene K, Dworkin RH, Rowbotham MC. A snapshot and scorecard for analgesic clinical trials for chronic pain: the RReACT database. Pain, 2012;153:1794-1797.
Munch M, Dufka FL, Greene K, Smith SM, Dworkin RH, Rowbotham MC. RReACT goes global: perils and pitfalls of constructing a global open-access database of registered analgesic clinical trials and trial results. Pain, 2014;155:1313-1317.
News
February 27, 2024: Second ABC Presentation
Kelley Kidwell, PhD, Professor of Biostatistics, University of Michigan, delivered the second presentation for the ACTTION Biostatistics Charrette (ABC). A recording of her presentation, “Study Design Considerations for Rare Phenotypes/Diseases,” is found here.
November, 2023: ACTTION Reaches Milestone of 175 Publications
September, 2022: ACTTION Awarded New FDA Grant
ACTTION has been awarded a cooperative agreement for 9/2022-8/2027 that expands its activities to address FDA’s Pediatric Anesthesia Safety Initiative.
September, 2021: ACTTION Guide to Clinical Trials of Pain Treatments
The ACTTION Guide to Clinical Trials of Pain Treatments consists of two supplements in Pain Reports. Part I includes 9 articles found here, and Part II includes 6 articles found here.