RReACT Database

The Repository of Registered Analgesic Clinical Trials (RReACT) database provides a snapshot of registered analgesic clinical trials and a scorecard for public availability of results. An overview of the RReACT database is provided by Greene et al. (2012), an update and global expansion is described by Munch et al. (2014), and the inclusion of two additional chronic pain conditions is presented by Dufka et al. (2015). Links to websites listed in the database may not still be active, and some studies may have had full publication of results since the most recent updating of the database. Links to the most recent version of the database follow:

Central post-stroke pain

Complex regional pain syndrome

Fibromyalgia database

Painful diabetic peripheral neuropathy (DPN) database

Postherpetic neuralgia (PHN) database

Dufka FL, Munch T, Dworkin RH, Rowbotham MC. Results availability for analgesic device, complex regional pain syndrome, and post-stroke pain trials: comparing the RReADS, RReACT and RReMiT databases. Pain, 2015;156:72-80.

Greene K, Dworkin RH, Rowbotham MC. A snapshot and scorecard for analgesic clinical trials for chronic pain: the RReACT database. Pain, 2012;153:1794-1797.

Munch M, Dufka FL, Greene K, Smith SM, Dworkin RH, Rowbotham MC. RReACT goes global: perils and pitfalls of constructing a global open-access database of registered analgesic clinical trials and trial results. Pain, 2014;155:1313-1317.